Synthesis and properties of pyrazolilimines.

Abstract

4-Pyrazolilimines are important intermediates for the creation of synthetic drugs. Considering their availability, the wide variety of possibilities of the pyrazole nucleus and the endocyclic imino function, and the high reactivity in addition to cyclo condensation reactions, the development of new heterocyclic derivatives based on them is a scientifically justified and topical task. The aim of the study. Develop conditions for synthesizing pyrazolyl imines with an amino group in position 5 of the pyrazole core, functionalized with ester and aldehyde groups in positions 3 and 4, respectively. Materials and Methods. All reagents were of "reagent" grade and were used in the experiments without further purification. All solvents used in this work were purified according to standard methods. Initial 4-pyrazolecarbaldehydes were synthesized by experimental methods.