Ontogenetic transformations of the pelvicalyceal system of the kidney from 5 to 9 weeks of the human prenatal ontogenesis.

Abstract

Clarifying the sources of the rudiments, features of morphogenesis and syntopic changes of organs and body structures at an early period of human ontogenesis is an important task of anatomists, histologists and embryologists. A clear understanding of the sequence of the main stages of embryogenesis and the temporal dynamics of structural transformations of the urinary system sources in the intrauterine period of human intrauterine development (IUD) will allow practicing doctors to clearly understand the features of the eriopathogenesis of malignant neoplasms of its organs and structures, to differentiate the remnants of embryonic tissues in the surgical material from tumors, to rationally apply the immunohistochemistry method in cancer diagnosis. The aim of the study. To determine the peculiarities of the rudiments sources and the chronological sequence of topographical and anatomical transformations of the organs and structures of the human urinary system. Materials and methods. The material for the study was 18 series of consecutive histological sections of specimens of human embryos and prefetuses (7.0-36.0 mm parietal-coccygeal length (PCL)) aged from 5 to 9 weeks of IUD. A complex of modern methods of morphological research (anthropometry, morphometry, microscopy, 3D computer reconstruction, statistical analysis) was applied.