Investigation of the potential enhancements in the diagnosis of the etiological factors associated with eczema through the implementation of patch testing in patients.

Abstract

Eczema is a common multifactorial dermatosis that develops on the background of multivalent sensitization to various chemical, biological, and other allergens. Genetic predisposition to allergies, impaired skin barrier function, changes in immune and neuroendocrine regulation, imbalance of prooxidant-antioxidant homeostasis, chronic infection, metabolic disorders, changes in skin microcirculation, etc. play a significant role in the onset and course of eczema. In recent years, eczema has tended to have a more severe clinical course with widespread skin lesions, frequent relapses, and torpidity to basic treatment, which reduces the ability to work, quality of life, and social activity of patients. All of this determines the medical and social significance of eczema and the relevance of optimizing its diagnostic program for clinical and laboratory examination of patients with eczema in order to identify all possible etiopathogenetic factors of dermatosis and develop more effective treatment and prevention measures for such patients. The aim of the study. Study the possibilities of improving the diagnosis of etiological factors of eczema development and recurrence by conducting patch testing of patients