Correlation relationship between biochemical indicators in umbilical cord blood samples depending on the inherited group and the mother’s Rh(D0) factor.

Abstract

Isoimmune hemolytic disease of the newborn is mainly observed when the mother has blood group 0(I) according to the AB0 blood group system, and in the fetus or newborn, according to the degree and frequency of inheritance A(II), B(III), and is the most common manifestation of the nosology of newborns. The initial stage of nosology is an increase in the level of total bilirubin (its indirect fraction). It is undeniable, that the most severe form of hemolytic disease develops as a result of incompatibility of the mother and the fetus according to the Rh(D) factor. Presumably, even in the case of absence of the development of newborns’ hemolytic disease, babies born to mothers with 0(I) blood group regardless of the Rh(D) factor and mothers with an Rh(D)-negative factor regardless of group affiliation according to the AB0 system will have changes in basic biochemical indicators of umbilical cord blood, depending on the inherited group and the mother's Rh(D) factor. The aim of the study. To investigate possible correlational relationships between the biochemical parameters of umbilical cord blood depending on the inherited group (according to the AB0 system) and Rh(D) factor (according to Rh(D0)) of the mother in infants without signs of hemolytic disease.