Cerebroprotective effect of substance ZNM

Abstract

Traumatic brain injury (TBI), the frequency and severity of which has increased today, is one of the main causes of mortality and disability. Given the hypoxic component of TBI and damage to the metabolism of nervous tissue during it, the use of antihypoxant protective agents is appropriate. Despite the fact that antihypoxants serve as means of etiotropic treatment of TBI, they can be used in the complex therapy of the consequences of brain injury and prevention of secondary brain damage. The aim of the study was to establish the impact of 2-benzamido-2-(2-oxoindolin-3-iliden) acetic acid derivative ZNM on the activity of pro-oxidant-antioxidant balance in TBI rats.