Indicators of the bronchial lability and hyperreactivity in children with bronchial asthma and exercise induced bronchoconstriction

Abstract

The results of the analysis of the bronchial hyperreactivity indicators in 60 children suffering from asthma with exercise induced bronchoconstriction and without exercise induced bronchospasm are presented in the article. It has been established that higher bronchial lability was typical for children with asthma and exercise induced bronchoconstriction. The bronchial hypersensitivity to inhaled histamine in a concentration less than 0,4 mg/ml with 77 % specificity, 71 % post-test probability and significant odds ratio indicate a phenotype of childhood asthma with exercise induced bronchoconstriction.