Characteristics of changes in the density of endothelial cells in the vessels of the frontal lobe cortex of the cerebral hemispheres in rats with diabetes under conditions of ischemia-reperfusion

Abstract

More than one million diabetes mellitus (DM) patients are officially registered in Ukraine, but the actual number of people with undiagnosed pathology exceeds this number by 3-4 times. One of the main causes of mortality in patients with diabetes is cardiovascular complications, in particular, impaired cerebral circulation. There are no reports in the scientific literature on the early and delayed effects of ischemia-reperfusion on the endothelial cell density in the vessels of the frontal lobe cortex of the hemispheres against the background of DM. The aim of the study. To study the features of changes in the density of endothelial cells of the frontal lobe cortex of the cerebral hemispheres before incomplete global ischemia-reperfusion under the conditions of streptozotocin-induced diabetes.