The anatomical relations and formation of physiological atresia In human embryogenesis

Abstract

The process of physiological atresia is inherent in the digestive, respiratory, genitourinary and biliary systems, as well as in the natural openings of the head - the eye slit, external nasal openings, external and internal auditory canals. This phenomenon is a natural process in the development of the organism in the early stages of prenatal human ontogenesis. Tubular organs and openings temporarily lose their lumen, and then recanalization occurs that is restoration of the cavity of the organ, duct, or opening. The disappearance of epithelial occlusion has a close correlation with the formation of villi and restructuring of the epithelial layer, at this time mesenchyme tissue with vessels penetrates the epithelium from the side of the intestinal wall. The aim of the study. To find out the peculiarities of the syntopy and trace the chronological changes morphometric parameters of the physiological atresia of human embryogenesis. Material and methods. The study was conducted on 24 embryos 4.0-12.0 mm PCL; 22 prenatal period of 14.0-78.0 mm PCL; 14 newborns. Series of histological, topographical and anatomical sections, morphometric, microscopic, histological, reconstruction and statistical methods were used for the research.