Combined use of sorbilact and L-arginine in endogenous intoxication syndrome.

Abstract

Correction of the syndrome of endogenous intoxication (SEI) is an important pathogenetic method of treating patients with purulent-septic complications. Despite the use of extracorporeal detoxification methods, infusion therapy remains the basis of the basic program of complex intensive therapy of SEI. Among drugs with pronounced detoxification properties, an important place belongs to solutions containing polyatomic alcohols, in particular sorbilact. The drug has a wide range of positive characteristics, and its effectiveness has been clinically established. The use of L-arginine together with sorbilact hides a significant potential as an activator of the toxin-releasing function and a nephroprotector. The aim of the study. To establish the effect of the combined use of sorbilact and L- arginine under the condition of standard therapy on the detoxification function of the kidneys and the level of MSI indicators.