Dyspeptic syndrome depending on the use of non-steroidal anti-inflammatory drugs in patients with osteoarthritis and concomitant non-steroidal gastroduodenopathies.

Abstract

he problem of gastroduodenopathies (GDP) caused by nonsteroidal anti- inflammatory drugs (NSAIDs) does not lose its significance. Nonsteroidal GDP are diagnosed in about 70% of patients who systematically use these drugs. It should be especially emphasized that there is no clear connection between subjective (symptomatic) side effects, endoscopically detected ulcers, and severe complications. Moreover, it seems that in patients without symptomatic side effects, ulcerative lesions of the stomach during endoscopy are found with the same frequency or even more often than in patients with these effects. The aim of study. To study the manifestations of dyspeptic syndrome in GDP caused by NSAIDs in patients with osteoarthritis (OA), depending on the structure of NSAID consumption, the degree of damage to the digestive tract and concomitant Helicobacter pylori.