Порівняльна характеристика антимікробної активності антибіотиків і поверхнево-активних речовин

Abstract

There was researched the activity in vitro of antibiotics benzylpenicillin, cefazolin and surface activity substance etony separately and in combinations with respect to strains Staphylococcus aureus 209, Escherichia coli K-12 and resistance strain Staphylococcus aureus. There was established the obvious increasing of the activity of the com positions KA (benzylpenicillin+etony) and КБ (cefazolin+etony). On the E. coli K -12 in KA for both components in 4 tims, in КБ – 8 times. On the S. aureus 209 in KA for etony in 16 and for benzylpenicillin in 2 times, in КБ – for both components in 4 times. On resistance strain S. aureus in KA for benzilpenicillin in 32 and for etony in 8 times, in КБ for etony in 4 and cefazolin in 8 times. Considerable discreasing of MIC compositions is expleined by the potential action of the activity, but not by the summation of the action of the latters.