POLYFUNCTIONAL PYRAZOLES. 10*. SYNTHESIS OF 5-OXO-4,5,7,9-TETRAHYDROPYRAZOLO[3,4-е][1,2,3]- TRIAZOLO[1,5-а][1,3]DIAZEPINE-3-CARBOXAMIDES IN A TANDEM REACTION OF ETHYL 4-(AZIDO- METHYL)PYRAZOLE-3-CARBOXYLATES WITH CYANOACETAMIDES

Abstract

4-(Azidomethyl)pyrazole-3-carboxylic acid ethyl esters react with cyanoacetamides in THF solution in the presence of t-BuOK resulting in the formation of 5-oxo-4,5,7,9-tetrahydropyrazolo[3,4-e][1,2,3]-triazolo[1,5-a][1,3]diazepine-3-carboxamides.