Novel Genetics and Humoral Prognostic Markers of Left Ventricle Hypertrophy in Hypertensive Patients

Abstract

Aim: The aim is to evaluate the echocardiographic (Echo-CG) changes in patients with EAH depending on genes AGT (rs4762), GNB3 (rs5443), and some humoral markers. Conclusion: The polymorphic variants of the AGT (521 C>T) and GNB3 (825 C>T) genes are associated with myocardial structure changes in EAH patients. Hypovitaminosis D in hypertensive individuals is accompanied by LVM and LVMI increase but reliably only in women.