Glutathione S-transferase T1 and M1 null genotype distribution among non-alcoholic fatty liver disease patients and its association with cytokine and adipokine profiles

Prysyazhnyuk, Vasyl; Voloshyn, Olexander; Prysiazhniuk, Iryna; Ilashchuk, Tetiana; Sydorchuk, Larysa; Prysyazhnyuk, Petro

dc.contributor.author	Prysyazhnyuk, Vasyl
dc.contributor.author	Voloshyn, Olexander
dc.contributor.author	Prysiazhniuk, Iryna
dc.contributor.author	Ilashchuk, Tetiana
dc.contributor.author	Sydorchuk, Larysa
dc.contributor.author	Prysyazhnyuk, Petro
dc.date.accessioned	2025-02-25T10:14:01Z
dc.date.available	2025-02-25T10:14:01Z
dc.date.issued	2020
dc.identifier.other	DOI: https://doi.org/10.5114/ceh.2020.95678
dc.identifier.uri	http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/26220
dc.description.abstract	Aim of the study: Among the key genes involved in the development of non-alcoholic fatty liver disease (NAFLD) are genes encoding the synthesis of glutathione S-transferase (GST). Conclusions: Deletion polymorphism of GSTT1 and GSTM1 genes distribution among NAFLD patients did not diﬀer as compared to healthy individuals. Null-genotype GSTT1 gene carriers were characterized by higher TNF-α concentration and null-genotype GSTM1 gene carriers were characterized by elevated leptin level as compared to normal genotype carriers.	uk_UA
dc.language.iso	en	uk_UA
dc.publisher	Clinical and Experimental Hepatology (офіційний журнал Польської асоціації з вивчення печінки)	uk_UA
dc.subject	non-alcoholic fatty liver disease	uk_UA
dc.subject	glutathione S-transferase gene	uk_UA
dc.subject	leptin	uk_UA
dc.subject	adiponectin	uk_UA
dc.title	Glutathione S-transferase T1 and M1 null genotype distribution among non-alcoholic fatty liver disease patients and its association with cytokine and adipokine profiles	uk_UA
dc.type	Article	uk_UA