Von Willebrand factor immunohistochemical staining quantitative optical density parameters in the endothelium and fibrinoid of the placenta during secundines inflammation and concomitant iron deficiency anemia in gravidas

Abstract

The aim of the research was to set the optical density quantitative parameters of the von Willebrand factor immunohistochemical staining (vWF) in the endothelium and fibrinoid of the placenta during the secundines inflammation concomitant with iron deficiency anemia in gravidas. Consequently, the optical density of the staining significantly increases in the endothelium of blood vessels in all forms of the secundines inflammation, in comparison with the physiological pregnancy, whereas in fibrinoid the same process is reported only in chronic course. In this case, IDAG is accompanied by maximum levels of optical density in the endothelium and fibrinoid, whereas in chronic, the average indices are higher than those in acute forms