Аннотации:
Lately more and more crucial diagnostic methods of the
functional state of endothelium in liver disease, chronic obstructive
pulmonary diseases, coronary heart disease, diabetes, hypertension and
others assume ever greater topicality. The data obtained are useful for
assessing the degree of severity of disease and to monitor therapeutic
measures. However, there are no information in the literature devoted to
studying the functional state of endothelium in HIV-infection/AIDS. So
far, the search for fundamentally new approaches to integrated diagnosis
of endothelial dysfunction in patients with HIV/AIDS and investigation
of their relationship with severity, presence of opportunistic infections
is continued. We know that it is quite different from the traditional
approach to studying the functional state of endothelial vascular wall -
definition of blood substances that are synthesized in endothelial cells
and secreted them in the lumen, and consequently in circulating blood.
Thus the questions of diagnosis and prognosis of HIV/AIDS remain
urgent and require further research.
