A mathematical model of transport kinetics of 99mTc radiotracers. An intravenous administration

Abstract

Abstract. The proposed four-compartment mathematical model describes transport kinetics of 99m-technetium radiotracers at intravenous administration process with taking into account radiopharmaceutical accumulation, elimination and radioactive decay. The dependencies of the tracer concentration versus the time are analyzed. The obtained data can be used to determine the transport coefficients. The model can be used for individual transport parameter calculation at administration of diagnostic/therapeutic dose loads.