Functional links in the brain cortex of kindled rats evaluated at different stages of kindling seizures precipitation

Abstract

Annotation. The work investigated the relationships between brain structures established in different periods of pentylenetetrazol (PTZ)-induced kindled seizure precipitation. As structures for investigations, the cortical ones of both hemispheres and the paleocerebellar cortex (VI-VII lobules) were chosen. Usage of these structures was explained by the well-known role of cortical neuronal population in spike-wave rhythm generation as well as the ‘antiepileptic’ properties of paleocerebellum.