СЕКЦІЯ 19. Фармакологічна дія та фармакокінетика лікарських засобів: Recent submissions

  • Study of the toxic influence of certain medicinal plants on the organism of rats 
    Rovinskyi, O.O. (Буковинський державний медичний університет, 2023)
    An important characteristic in the process of a potential drug research in addition to the therapeutic properties examitation is studying the index LD50, which characterizes the degree of drugs toxicity, the range of its ...
  • Pharmaceutical pollution in Ukraine 
    Pazyniuk, A.Yu. (Буковинський державний медичний університет, 2023)
    As the population of our planet continues to grow, so does the need for adequate medical supplies, including chemical-based medicines and care products. Their significant therapeutic effect does not go unnoticed in our ...
  • Study of anti-inflammatory activity of altabor substances 
    Muzyka, N.Y. (Буковинський державний медичний університет, 2023)
    The inflammatory process is considered to be one of the evidenced causes in pathogenesis of prostate disease. The essential requirement for new products with prostprotoprotective effect is suppression of inflammation.
  • Nephrotropic effects of emoxipine under the conditions of chronic hypoxic hypoxia 
    Melnychuk, S.P. (Буковинський державний медичний університет, 2023)
    Free radical oxidation is the most important regulator of lipid and protein metabolism. The result of the intensification of free-radical oxidation, conditions for which are created even in hypoxia, is an increase in the ...
  • Comparative analysis of indicators of the total risk of illness and death from hodgkin's lymphoma and its five-year prevalence in Ukraine and Poland 
    Matushchak, M.R. (Буковинський державний медичний університет, 2023)
    Hodgkin's lymphoma (HL) is a severe disease that affects the most able-bodied population groups in society and has severe consequences for human health. In addition, considerable resources are spent on the treatment of ...
  • Research of medicinal properties saponaria officinalis 
    Kostyshyn, L.V. (Буковинський державний медичний університет, 2023)
    The pharmaceutical industry, despite the large range of products, pays great attention to the study of plant raw materials, since phytoremedies are better absorbed by the human body and have practically no side effects. ...
  • Study of the fever-induced changes in kidney function 
    Kopchuk, T.G. (Буковинський державний медичний університет, 2023)
    Kidney and urinary tract diseases, especially of microbial-inflammatory origin, occupy one of the leading places in the structure of somatic pathology. The kidneys play an important role in the maintaining homeostasis, ...
  • The influence of lipin on the functional status of the kidneys in rats under the conditions of the glycerol model of acute renal failure with long-term use 
    Horoshko, О.М. (Буковинський державний медичний університет, 2023)
    The topical direction of modern medicine is the use of drugs with minimal side effects. A promising direction of increasing the selectivity of the action of the medicinal product is the creation of a carrier capable of ...
  • Experimental study of the kidney functions changes after pharmacological activation of potassium channels 
    Filipets, N.D. (Буковинський державний медичний університет, 2023)
    Adenosine triphosphate-sensitive potassium (KATP) channels of cell membranes play a special role in the mechanisms of restoration of disturbed oxygen homeostasis of the body. Their opening in response to a decrease in the ...
  • Results of statistical analysis of data of patients with alzheimer's disease 
    Fedotova, M.S. (Буковинський державний медичний університет, 2023)
    Taking into account the urgency of the process of reforming the national health care system in the direction of implementing rational models of resource provision for patients, including the psychoneurological direction, ...
  • Prospects for the use of phytopreparations in the treatment of type 2 diabetes 
    Ezhned, M.A. (Буковинський державний медичний університет, 2023)
    Diabetes mellitus type 2 is a chronic endocrine disease characterized by persistently elevated blood glucose levels and impaired insulin tolerance. Diabetes mellitus type 2 counts for 90-95% of all reported cases of diabetes. ...
  • Morphological changes of kidney tissue when using hepaval in ischemia-reperfusion acute kidney injury 
    Drachuk, V.M. (Буковинський державний медичний університет, 2023)
    Ischemia-reperfusion injury, which is usually caused by trauma, sepsis, kidney transplantation, exposure to toxic substances, primarily affects the structure and function of the cells of the tubular epithelium, which is ...
  • HPLC-dad assay of phenols profile in ANTENNARIA DIOICA (L.) Gaertn 
    Basaraba, R.Y. (Буковинський державний медичний університет, 2023)
    Antennaria dioica (L.) Gaertn. (A. dioica, Stoloniferous Pussytoes) is the plant belonging to the same tribe (Gnaphalieae) of the Asteraceae family. It is a perennial herb, commonly found in dry grasslands and sandy or ...

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