Peculiarities of lamina cribrosa thickness in patients with proliferative diabetic retinopathy after vitrectomy with silicon oil tamponade and retrolaminar migration of silicon oil

Abstract

For ~40 years, silicone oil (SiO) is accepted as an effective treatment used as an intraocular tamponade in the pars plana vitrectomy, especially in cases of complicated retinal detachments. Retrolaminar SiO migration is a benign complication of intraocular SiO injections, occurring when the SiO diffuses posteriorly into the structures of visual pathway (optic nerve, optic chiasm, optic tract, lateral cerebral ventricles). The mechanism is still under debate, but it has been suggested elevated intraocular pressure, macrophages or optic nerve head anatomical predispositions as potential explanations. Recent studies suggest that SiO may infiltrate or diffuse directly into the retinal layers and then into the optic nerve by infiltrating along the retinal nerve fibers through the lamina cribrosa (LC). found on plasminogen.