Theoretical Description for Omeprazole Cathodical Electrochemical Determination, Assisted by Omeprazole Electrochemical Determination, Assisted by the Composite Poly(1,2,4-triazole) – VO(OH)

Tkach, Volodymyr V.; Kushnir, Marta V.; Kopiika, Vira V.; Luganska, Olga V.; Omelianchyk, Lyudmyla O.; Kormosh, Zholt O.; Kryvetskyi, Viktor V.; Kryvetskyi, Igor V.; Kryvetska, Inna I.; Honchar, Tetiana V.; Rotar, Gabriella P.; Ostapchuk, Valentyna G.; Melnychuk, Svitlana P.; Ivanushko, Yana G.; Gordiyenko, Natalia M.; Britsyna, Yulia V.; Bagrii, Konon L.; Strutynska, Lyubov T.; Danyliuk, Inna P.; De Oliveira, Sílvio C.; Yagodynets, Petro I.; Razhabova, Dilafruz B.; Niyazov, Laziz N.; Odyntsova, Vira M.

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Theoretical Description for Omeprazole Cathodical Electrochemical Determination, Assisted by Omeprazole Electrochemical Determination, Assisted by the Composite Poly(1,2,4-triazole) – VO(OH)

Tkach, Volodymyr V.; Kushnir, Marta V.; Kopiika, Vira V.; Luganska, Olga V.; Omelianchyk, Lyudmyla O.; Kormosh, Zholt O.; Kryvetskyi, Viktor V.; Kryvetskyi, Igor V.; Kryvetska, Inna I.; Honchar, Tetiana V.; Rotar, Gabriella P.; Ostapchuk, Valentyna G.; Melnychuk, Svitlana P.; Ivanushko, Yana G.; Gordiyenko, Natalia M.; Britsyna, Yulia V.; Bagrii, Konon L.; Strutynska, Lyubov T.; Danyliuk, Inna P.; De Oliveira, Sílvio C.; Yagodynets, Petro I.; Razhabova, Dilafruz B.; Niyazov, Laziz N.; Odyntsova, Vira M.

URI: http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/20687

Дата: 2021

Аннотации:

Abstract: In this work, we describe theoretically the possibility of omeprazole electrochemical determination, assisted by the composite containing vanadium oxyhydroxide as an active substance and the polymer of 1,2,4-triazolic derivative as a mediator. The omeprazole molecule undergoes a sulfoxide to sulfide reduction process over a trivalent vanadium compound. The vanadium oxyhydroxide, at its turn, may be oxidized to a tetravalent state, represented in two forms. The electroanalytical process behavior will be illustrated by a trivariate equation-set, analysis of which confirms the efficiency of the composite of poly (1,2,4-triazole) with VO(OH). Vanadium (III) oxyhydroxide may be efficiently used for omeprazole detection both in pharmaceutical formulations, food, and biological liquids.

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