Abstract:
Abstract. One of the main complications during early embryogenesis and placentation is placental dysfunction. Different factors, and infectious in particular, depending on their biological specificity produce a negative effect on reproductive cells of parents, development of the embryo, formation of trophoblast and placenta, that results in functional disorders of the placental complex and gestational complications during pregnancy. Due to extension of diagnostic possibilities to find functional disorders of the placenta as well as appearance of new data concerning the mechanisms of regulation of placental blood circulation in order to assess functional state of the fetal-placental complex (FPC) at the stage of formation of primary placental dysfunction against the ground of inflammatory diseases of the female reproductive organs we have determined Doppler image of the blood flow peculiarities (ovarian artery, intervillous space) in the women of the main and control groups. According to the stated purpose we have conducted ultrasound examination of 67 women at 6-7 and 12-14 weeks of gestation. The main group included 37 women with the signs of inflammatory diseases of the female reproductive organs, and the control group included 30 practically healthy women. Оbtaining new data concerning the mechanisms to regulate blood circulation in the ovarian artery and intervillous space at the stage of formation of the placental complex in case of physiological and complicated pregnancy will enable to supplement the issues of pathogenesis and prevention of placental dysfunction.
