Caspase-3 and Caspase-8 in Patients with Nodular Goiter and Autoimmune Thyroiditis

dc.contributor.author	Sheremet, М.I.
dc.contributor.author	Shidlovskyy, V.O.
dc.contributor.author	Sydorchuk, L.P.
dc.contributor.author	Sydorchuk, R.I.
dc.date.accessioned	2022-03-29T11:39:56Z
dc.date.available	2022-03-29T11:39:56Z
dc.date.issued	2016
dc.identifier.uri	http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19407
dc.description.abstract	Abstract. The article presents results of the comparative analysis of peroxidation process activity of caspase-3 and caspase-8 in patients with thyroid adenoma (ТА) and nodular goiter with autoimmuune thyroiditis (NGAIT). Studying peroxidation processes in the tissue of the thyroid gland abnormal tissue was detected to be characterized by increase in of protein oxidative modification (POМ) indices at the same time, the antioxidant enzymes activity (AEA) was significantly reduced and was more likely in patients with NGAIT. Significant increase in activity of both caspase 3 and 8 was shown in patients with NGAIT compared to macroscopically unchanged tissue and thyroid adenoma. Possible mechanisms of the detected disorders were discussed.	uk_UA
dc.language.iso	en	uk_UA
dc.publisher	Галицький лікарський вісник	uk_UA
dc.subject	nodular goiter with autoimmune thyroiditis	uk_UA
dc.subject	thyroid adenoma	uk_UA
dc.subject	apoptosis	uk_UA
dc.subject	peroxidation	uk_UA
dc.subject	caspase 3	uk_UA
dc.subject	caspase 8	uk_UA
dc.title	Caspase-3 and Caspase-8 in Patients with Nodular Goiter and Autoimmune Thyroiditis	uk_UA
dc.type	Article	uk_UA