Abstract:
There was researched the activity in vitro of antibiotics benzylpenicillin, cefazolin and surface activity substance etony separately and in combinations with respect to strains Staphylococcus aureus 209, Escherichia coli K-12 and resistance strain Staphylococcus aureus.
There was established the obvious increasing of the activity of the com positions KA (benzylpenicillin+etony) and КБ (cefazolin+etony). On the E. coli K -12 in KA for both components in 4 tims, in КБ – 8 times. On the S. aureus 209 in KA for etony in 16 and for benzylpenicillin in 2 times, in КБ – for both components in 4 times. On resistance strain S. aureus in KA for benzilpenicillin in 32 and for etony in 8 times, in КБ for etony in 4 and cefazolin in 8 times.
Considerable discreasing of MIC compositions is expleined by the potential action of the activity, but not by the summation of the action of the latters.
