The foundations of the traditional Müller-matrix polarimetry are set forth in a series of publications. A new step was the basics of laser polarimetry of optically thin nondepolarizing layers creation. The question of studying the optical anisotropy of diffuse depolarizing layers remains open. This work is aimed at the development and substantiation of the methods of Muellermatrix mapping and 2D reconstruction of distribution of parameters of linear and circular dichroism of mice liver tissue with different degrees of severity of diabetes.