Аннотации:
Schizophrenia patients frequently develop somatic co-morbidity.
Schizophrenia is a complex disorder, with a high heritability, yet little is
known about the underlying mechanisms. The etiology involves multiple
genes, interacting biological pathways, and a variety of environmental
risk factors. Schizophrenia is, however, increasingly recognized as a
systemic disorder and these patients face an additional burden in terms of
somatic comorbidity implying overlapping and interacting disease
mechanisms that involve neurotransmitter, inflammatory, endothelial and
hormonal pathways among others. Patients suffering from schizophrenia
and related psychoses run a substantial risk of developing diabetes
mellitus, metabolic syndrome, hypertension, cardiovascular diseases,
lung diseases such as COPD, hypothyroidism and visual problems.
