Abstract:
Our works consider the investigation of possible manifestation of hyperbilirubinemia in infants against the ground of genetic incompatibilities of the fetus according to АВ0 system and Rh-factor (D) concerning the maternal organism. From this point of view we deal with jaundice of mixed genesis against erythroblastosis domination as a primary antenatal factor of pathological process formation. The present study presents the results of distribution of the group and rhesus determinants (Rh D) of infants born to mothers with negative Rh-factor in 2014. Analytical review and comparison with the previous investigations in this direction have been made. New trends of further work with the elements of chronobiological characteristics concerning possible signs of hemolytic diseases of newborns (HDN), neonatal isoerythrolysis, in Bukovyna region are outlined. The values of umbilical bilirubin concentration are taken as a biochemical criterion of HDN development which is the main diagnostic sign of pathological jaundice of newborns. The signs of HDN of various degree were observed in 24 infants out of 333 neonates born to mothers with negative Rh-factor during the period of 2014.
