Changes of glutathione system parameters in blood of alloxan diabetic rats under the influence of melatonin in condition of light around-the-clock

Яремій, Ірина Миколаївна; Кушнір, Олександра Юріївна; Харченко, Аліна Олександрівна

dc.contributor.author	Яремій, Ірина Миколаївна
dc.contributor.author	Кушнір, Олександра Юріївна
dc.contributor.author	Харченко, Аліна Олександрівна
dc.date.accessioned	2016-07-18T12:25:29Z
dc.date.available	2016-07-18T12:25:29Z
dc.date.issued	2016-04
dc.identifier.isbn	978-3-946407-01-0
dc.identifier.uri	http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/11108
dc.description.abstract	Insertion of melatonin for 7 days helped to reduce 1,7 times basal glucose level in the group of animals with overt diabetes in condition of light around-the-clock. Activity of glucose-6-phosphate dehydrogenase, glutathione peroxidase and glutathione reductase in the blood of rats with overt diabetes was on 45%, 32%, and 30% respectively lower than in control rats that were under artificial equinox. In rat blood with overt and latent diabetes occurred reduction of reduced glutathione content on 23% and 42% respectively compared with those of control. Insertion of melatonin to diabetic rats helped in normalization of parameters.	ru_RU
dc.description.sponsorship	Кафедра біоорганічної і біологічної хімії та клінічної біохімії	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Deutscher Wissenschaftsherold – German Science Herald	ru_RU
dc.relation.ispartofseries	;№1
dc.subject	melatonin	ru_RU
dc.subject	alloxan diabetes	ru_RU
dc.subject	glutathione system	ru_RU
dc.subject	blood	ru_RU
dc.subject	rats	ru_RU
dc.subject	light around-the-clock	ru_RU
dc.title	Changes of glutathione system parameters in blood of alloxan diabetic rats under the influence of melatonin in condition of light around-the-clock	ru_RU
dc.type	Article	ru_RU