Effect of melatonin on the functioning of glutathione system in the liver of alloxan diabetic rats in lighting conditions around the clock

Яремій, Ірина Миколаївна; Кушнір, Олександра Юріївна; Харченко, Каріна Олександрівна

dc.contributor.author	Яремій, Ірина Миколаївна
dc.contributor.author	Кушнір, Олександра Юріївна
dc.contributor.author	Харченко, Каріна Олександрівна
dc.date.accessioned	2016-07-18T12:18:15Z
dc.date.available	2016-07-18T12:18:15Z
dc.date.issued	2016-01-31
dc.identifier.issn	2308 - 1996
dc.identifier.uri	http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/11106
dc.description.abstract	Abstract. Insertion of melatonin for 7 days helped to reduce 1,7 times basal glucose level in the group of animals with overt diabetes. Activity of glucose-6-phosphate dehydrogenase, glutathione peroxidase and glutathione reductase in the liver of rats with overt diabetes was on 47%, 33%, and 35% respectively lower than in control rats that were under artificial equinox. In rat liver with overt and latent diabetes occurred reduction of reduced glutathione content on 25% and 41% respectively compared with those of control. Insertion of melatonin to diabetic rats helped in normalization of parameters.	ru_RU
dc.description.sponsorship	кафедра біоорганічної і біологічної хімії та клінічної біохімії	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Science and Education a New Dimension. NATURAL AND TECHNICAL SCIENCE	ru_RU
dc.relation.ispartofseries	IV (9), Issue: 83, P.71-74;
dc.subject	melatonin	ru_RU
dc.subject	alloxan diabetes	ru_RU
dc.subject	glutathione system	ru_RU
dc.subject	liver	ru_RU
dc.subject	rats	ru_RU
dc.title	Effect of melatonin on the functioning of glutathione system in the liver of alloxan diabetic rats in lighting conditions around the clock	ru_RU
dc.type	Article	ru_RU