Endothelium function biomarkers and carotid intima-media thickness changes in relation to NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphism in the essential arterial hypertension

Please use this identifier to cite or link to this item: http://dspace.bsmu.edu.ua:8080/jspui/handle/123456789/26487

Title:	Endothelium function biomarkers and carotid intima-media thickness changes in relation to NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphism in the essential arterial hypertension
Authors:	Sydorchuk, Andrii R. Sydorchuk, Larysa P. Gutnitska, Adelina F. Dzhuryak, Valentina S. Kryvetska, Inna I. Sydorchuk, Ruslan I. Ursuliak, Yulia V. Iftoda, Oksana M.
Keywords:	NOS3 (rs2070744) but not GNB3 (rs5443) gene associated with the essential arterial hypertension severity relying upon the endothelial function impairment and NOS3 genes reduced transcription activity
Issue Date:	2022
Publisher:	Endocrine Regulations (міжнародний журнал)
Abstract:	Objective. The aim of the present study was to clarify the endothelial function biomarkers and carotid “intima media” thickness (IMT) changes in relation to GNB3 (rs5443) and NOS3 (rs2070744) genes polymorphism in the essential arterial hypertension (EAH). Conclusion. NOS3 (rs2070744), but not GNB3 (rs5443), gene associated with the essential arterial hypertension severity relying upon the endothelial function impairment and NOS3 genes reduced transcription activity.
URI:	http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/26487
Appears in Collections:	Статті. Кафедра гігієни та екології

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