Взаємозв'язок тонусу та об’єму заповнення центральних вен у хворих на есенційну гіпертензію ІІ стадії за різної структури циркадіанного ритму АТ

Abstract

The aim – to improve the diagnosis of some forms of essential hypertension (EH) II stage based on study of the central venous tone, salt taste sensitivity, water and electrolyte exchange depending on circadian rhythm of blood pressure (BP). Material and methods. We studied the tone of venous vessels by data of central venous pressure (CVP) and compressiondecompression test on forearm using original methods, the threshold of a taste sensitivity to a salt (TSS), serum sodium concentration and daily sodium urine excretion in 84 patients with EH stage II and circadian structure of arterial pressure «D» – dipper, «ND» – non dipper and «NP» – night peaker. Results. According to the data of daily blood pressure monitoring, among all examined patients predominated persons with the low daily index – ND and NP, that was 52.4 % and 9.5 % respectively. In these groups arterial hypertension in most patients was associated with venous hypertension. Increase of TSS and urine sodium excretion indicate that arterial and venous hypertension is caused by hypervolumic type of the disease. Conclusions. Increase of the threshold of TSS and daily sodium urine excretion associated with moderate decrease of the daily diuresis in patients with non-dipper and night peaker circadian structure of blood pressure show that arteriovenous hypertension is caused by hypervolemic course of the disease.