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dc.contributor.authorKoloskova, O.K.en
dc.contributor.authorBilous, T.M.en
dc.contributor.authorMikaliuk, L.V.en
dc.contributor.authorOrtemenka, E.P.en
dc.date.accessioned2015-02-26T07:41:28Z
dc.date.available2015-02-26T07:41:28Z
dc.date.issued2014
dc.identifier.urihttp://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/8256
dc.description.abstractBased on a comprehensive survey of 150 school-age children who suffer from bronchial asthma, there has been found that homozygosity for both alleles of the gene of glutathione transferase (GSTT1+ M1+) was associated with more frequent use both inhaled corticosteroids at 3 Step 3 of basic therapy and leukotriene modifiers as well as better asthma control level according to the ACT-test. Under the presence of such genotypes as GSTT1+ M1-, GSTT1-M1+ or GSTT1-M1-, the basic treatment was more likely within 2-nd and 4-th Steps by GINA recommendations, but the level of asthma control was worse in these children.ru_RU
dc.language.isoenru_RU
dc.relation.ispartofseriesTHE PHARMA INNOVATION - JOURNAL ;Vol. 2 No. 12.
dc.subjectbronchial asthmaru_RU
dc.subjectchildrenru_RU
dc.subjectglutathione-S-transferaseru_RU
dc.titlePharmacogenetic aspects of basic anti- inflammatory therapy of bronchial asthma in school-aged children under the deletion polymorphism of genes Gstt1 and Gstm1ru_RU
dc.typeArticleru_RU
Appears in Collections:Статті. Кафедра педіатрії та дитячих інфекційних хвороб

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