Proteolytic plasma activity in diabetic patients with chronic impairment of cerebral circulation

Abstract

Diabetic patients with chronic impairment of cerebral circulation underwent measurement of the indices of plasma proteolytic activity. The inhibition of proteolytic destruction of low- and high-molecular proteins, accompanied by intensification of collagenolysis, was established, indicating the intensity of destabilization of cerebral atherosclerotic plaque. The obtained changes progressed with the stage of encephalopathy.