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Title: | Experimental assessment of carbacetam effect on the cerebral mitochondria in rats with scopolamine-induced Alzheimer’s disease |
Authors: | Kmet, Olga G. Filipets, Nataliia D. Yaremii, Iryna M. Kmet, Taras I. Vepriuk, Yurii M. Hrachova, Tamara I. |
Keywords: | carbacetam scopolamine-induced Alzheimer’s disease functional state of the mitochondria |
Issue Date: | 2020 |
Publisher: | Archives of the Balkan Medical Union (міжнародний рецензований міждисциплінарний журнал) |
Abstract: | The objective of the study was to evaluate the protective effect of carbacetam under conditions of mitochondrial dysfunction of the brain in rats with scopolamine-induced Alzheimer’s disease. Conclusions. Reduced intensity of mitochondrial swelling, improvement of the antioxidant system state and energy supply of mitochondria in the cerebral cortex and hippocampus of rats with scopolamine-induced Alzheimer’s disease are indicative of mitoprotective properties of carbacetam as a promising neuroprotector. |
URI: | http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/26464 |
Appears in Collections: | Статті. Кафедра гігієни та екології |
Files in This Item:
File | Description | Size | Format | |
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Kmet O.G. et al. Experimental_14-21_2020.pdf | 382.4 kB | Adobe PDF | View/Open |
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