Disease-modifying therapy in rheumatoid arthritis and changes in cytokine levels depending on genetic characteristics

Abstract

Abstract. Among the factors that influence the occurrence of rheumatoid arthritis, a complex interaction of genetic, environmental, immunological, hormonal, socio-economic and psychological prerequisites is noted. Genetic factors in interaction with the environment and an individual's lifestyle play an important role in changing gene expression and the clinical realization of inherited or acquired pathology, including multifactorial. That is why the study of genetic mutations and their association in patients with rheumatoid arthritis is important today not only from a scientific point of view, but also for practical health care.