Effect of physical rehabilitation on the oxidative modification of proteins in patients with ischemic heart diseases

Abstract

The aim of the study. Study the features of oxidative modification of proteins in patients with ischemic heart disease (IHD) on the background of treatment and assess the dynamic change of proteins at a high physical activity before and after the physical rehabilitation. Conclusion. 1. In patients with coronary artery disease detected increase in oxidative modification of proteins (p <0.001) positive correlation with the content of creatinine (r = 0,35) (p <0.05) and lactate dehydrogenase activity (r = 0,42) (p <0.05), and negative – of the total activity of creatine phosphokinase (r = -0,54) (p <0.05). After the physical rehabilitation according to our methodology of bicycle training reduced oxidative modification of proteins in the study group with a direct correlation with lactate dehydrogenase activity (r = 0,35) (p <0.05), indicating a decrease in metabolic acidosis and improve cell.