Antihypoxic activity of the derivative of 2-benzamido-2-(2-oxoindolin-3-iliden) acetic acid under the conditions of acute hypobaric hypoxia

Abstract

Hypoxia is a pathological condition that occurs when there is an insufficient supply of oxygen to tissues or disorder of oxygen uptake during the process of oxidation. It occurs under the conditions of oxygen deficiency in the environment, and as a result of various pathological processes and diseases associated with disorders of the respiratory and cardiovascular systems, the blood transport function or metabolism. Drugs affecting the metabolism during hypoxia – antihypoxants, which are agents that improve oxygen consumption by the body and reduce oxygen demand of tissues and organs, thereby increasing the body’s resistance to oxygen deficiency, are of particular interest (Zamorskii I.I., Bukataru Y.S., Kolisnyk S.V.et al., 2016).