Microbiome of vulvovaginal contents in women with primary infertility

Abstract

In most women, primary infertility is based on the tubo-peritoneal form of infertility, which was preceded by an infectious-inflammatory process of the reproductive organs (uterus, appendages). The taxonomic composition, population level and microscopic indicators of the microbiome of the vulvovaginal contents are in the dynamic balance of the microecological system "macroorganism-microbiome". Any disturbances in the macroorganism, including infertility, can lead to its disturbances, and vice versa, disturbances in species, population structure and ecosystem indicators can contribute to the formation of infertility.