Cytokines' mechanisms of immunological disorders in children with hearing loss depending on gene polymorphism interleukin-4 (rs2243250)

Abstract

Nowadays, about 360 million people worldwide suffer from hearing loss. Hearing loss can be caused by genetics, birth defects, certain infectious diseases, chronic ear infections, certain medications, exposure to excessive noise, etc. About 100 genes in the human body are responsible for the hearing organ formation and function. However, there are currently no guidelines for using of molecular genetic tests in the early diagnosis of deafness. The question of the impact of genetic factors on the features of the immune response depending on the type of deafness is also debatable.