Management of chronic wounds in modern conditions

Abstract

Chronic wounds occupy a leading position among diseases and hospitalization of patients in the department of purulent surgery. Such patients are characterized by long-term disability, expensive treatment, slow rehabilitation after treatment, or permanent disability. According to the World Health Organization, the main causes of wounds that do not heal for a particularly long time are insufficient blood flow in the wound, imbalance of inflammatory and reparative processes in the wound, microbial contamination and antibiotic resistance due to microbial biofilms, slowing down the formation of the demarcation wall, excess production of proteases and reduced activity of growth factors. Considering the above, the modern methods of treating chronic wounds that restore all the listed pathogenetic factors of long-term non-healing of such wounds are promising today.