Treatment and prevention of postoperative complications of diffuse peritonitis

Abstract

Peritonitis is one of the most serious complications of diseases and injuries of the abdominal cavity and consistently occupies a leading place in the structure of surgical mortality, which, according to various authors, ranges from 1.3% in case of local to 80% in case of widespread peritonitis. An important role in the pathogenesis of peritonitis is played by bacterial contamination of the peritoneum, qualitative and quantitative composition of microbial associations, as well as biological properties of microorganisms. One of the leading links of pathogenesis, which often leads to multiple organ failure and death in peritonitis, is endotoxicosis. Therefore, timely diagnosis of the level of endogenous intoxication and implementation of adequate detoxification therapy is important.