Features of the course of the joint syndrome in patients with comorbid nonalcoholic steatohepatitis and obesity

Abstract

An important problem is the comorbidity of NAFLD with obesity (OB) and osteoarthritis (OA), which is characterized by a burdening syndrome. The incidence of Ob, which affects 28-35% of the population of economically developed countries, has increased by 57% in recent years. Osteoarthritis of large joints is a common comorbid pathology on the background of OB. The urgency of the problem of studying OA is due to the high prevalence of OA, the rapid development of functional disorders and disability of people of all ages. Taking repeated courses of nonsteroidal anti-inflammatory drugs (NSAIDs), which are hepatotoxic drugs, negatively affects the course of nonalcoholic steatohepatitis (NASH).