Synthesis and antimicrobial activity of 4-nitroimidazole-5-thioacetic acid hydrazides

Abstract

In modern methodologies of the rational construction of new biologically active substances and leader compounds for the creation of medicinal products, imidazole-containing structures play a key role due to their powerful medical and biological potential. An important place among imidazoles is owned by various types of their functionalized derivatives, which are characterized by antibacterial, antifungal, anticancer, antituberculosis and mutagenic effects.