Будь ласка, використовуйте цей ідентифікатор, щоб цитувати або посилатися на цей матеріал:
http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/20433
Назва: | Significance of clinical and laboratory markers in disorders of the functional condition of the hepatobiliary system in neonatal jaundice |
Автори: | Volosivska, Yuliia Hodovanets, Yuliia Yurieva, Lilia |
Ключові слова: | newborn jaundice liver hepatobiliary system biochemical markers |
Дата публікації: | 2020 |
Видавництво: | CBU International Conference Website |
Бібліографічний опис: | СBU International Conference on Innovations in Science and Education 2020 (Medicine and Pharmacy), March 18-20, 2020, Prague |
Короткий огляд (реферат): | Introduction: The liver is the central organ of metabolic activity in the body. Objectives: The purpose of this study was to determine predictors, major clinical features, and laboratory criteria for the severity of disorders of the functional state of the hepatobiliary system in newborns with neonatal jaundice (NJ). The study included 164 full-term infants. The main group - 92 children, with manifestations of pathological jaundice, was divided into two subgroups, depending on the severity of the pathology, considering concomitant perinatal pathology. IA group (46 children) includes children, condition of which was defined as moderate, IB (46 children) – children, condition of which was defined as severe, the control group consisted of 72 healthy term infants. Conclusion: The results of the analysis of anamnestic and clinical-laboratory parameters in newborns with NJ showed on the background of a clinical signs of dysfunction of the hepatobiliary system, the presence of significant biochemical changes, especially enzymatic activity, including, ALT, AST, LDH, ALP, and γ-GT and, also an increase in TBS levels and an indirect bilirubin fraction, a decrease in total protein and albumin, glucose, a rise in urea, cholesterol and triglycerides. The use of a biochemical markers in newborns with clinical manifestations of neonatal jaundice, especially in cases of significant severity of the condition with concomitant perinatal pathology, requires more detailed analysis in order to determine the main pathogenesis of disorders of the functional state of the hepatobiliary system for the purpose of timely correction and improvement of the outcome of treatment. |
URI (Уніфікований ідентифікатор ресурсу): | http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/20433 |
Розташовується у зібраннях: | Статті. Кафедра акушерства, гінекології та перинатології |
Файли цього матеріалу:
Файл | Опис | Розмір | Формат | |
---|---|---|---|---|
Volosivska Yu, Hodovanets Yu, Yurieva L. Significance of clinical and laboratory markers_2020.pdf | 144.68 kB | Adobe PDF | Переглянути/Відкрити |
Усі матеріали в архіві електронних ресурсів захищені авторським правом, всі права збережені.