INFLUENCE OF SELENIOUM-CONTAINING MEDICINES ON CARBOHYDRATE METABOLISM IN PATIENTS WITH DIABETES MELLITUS

Abstract

Introduction. Diabetes mellitus is a metabolic disorder. About 4–5% of the world population suffers from diabetes. Obesity is considered as one of the strongest risk factors for type 2 diabetes manifestation. According to WHO, the prevalence of MS is 20-40%, thus receiving the characteristic of the "XXI century pandemia". The search for new ways of correction of carbohydrate metabolism is a promising direction. Objective.Improve treatment of carbohydrate metabolism disorders in patients with diabetes mellitus. Materials and methods. In order to determine the effect ofselenium-containing drugs on thyroid homeostasis indices in patients with diabetes mellitus type 2, we examined 65 patients who were randomized according to age and sex into two groups: 31 patients received basic therapy, 34 patients received selenium-containing ьувшсштуы in a dose equivalent to 50mcg of selenium per day against the background of standard treatment. Results.As a result of taking selenium on the background of basic treatment for 1 month, we have revealed an improvement in the state of carbohydrate metabolism comparing with control group - HOMA-IR (p <0,05). Conclusion. The obtained data suggestspositive effect of selenium containing medicines on background of standard treatment on carbohydrate metabolism by reduction of insulin resistance.