Biomedical applications of Jones-matrix tomography to polycrystalline flms of biological fuids

Abstract

Algorithms for reconstruction of linear and circular birefringence-dichroism of optically thin anisotropic biological layers are presented. The technique of Jones-matrix tomography of poly-crystalline flms ofbiological fuids ofvarious human organs hasbeendeveloped andexperimentallytested. The coordinate distributions of phase and amplitude anisotropy of bile flms and synovial fuid taken from the knee joint are determined and statistically analyzed. Criteria (statistical moments of 3rd and 4th orders) of di®erential diagnostics of early stages of cholelithiasis and septic arthritisoftheknee joint with excellent balance daccuracy were determined. Data on the diagnostic eciency of the Jones-matrix tomography method for polycrystalline plasma (liver disease), urine (albuminuria) and cytological smears (cervical cancer) are presented.