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dc.contributor.authorКричун, Ігор Іванович-
dc.contributor.authorПашковський, Валерій Мелетійович-
dc.date.accessioned2012-06-06T14:14:35Z-
dc.date.available2012-06-06T14:14:35Z-
dc.date.issued2012-05-
dc.identifier.urihttp://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/1534-
dc.description.abstractIt has been established that in patients with vegetovascular dystonia after the hypertensive type the blood content of sCD95 molecules decreases and the sCD117 level increases that is accompanied by a reliable elevation of the caspase-1 activity, however, the activity of caspases-3 and -8, as well as the blood content of sFas-l do not change. Multimodality treatment, employing glutargin decreases the plasma content of sCD95 by 28 %, normalizes the blood sCD117 level and does not influence on the sFas-l concentration and the activity of caspases-1,-3,-8 in the blood plasma. With vegetovascular dystonia after the hypotensive type the blood plasma concentration of sCD95, sFas-l and the activity of caspases-1,-3,-8 correspond to the control value against a background of an elevation of the plasma concentration of sCD117 by 91 %. The use of erbisol in the treatment does not change the plasma concentration of sCD95, sFas-l and the activity of caspases-1,-3,-8 and diminishes the blood content of sCD95 up to control values. The blood plasma concentration of the molecules of sCD95, sFas-l and a dissolved form of the factor of stem cells – sCD117 molecules increases statistically significantly in patients with VVD after the mixed type as compared with the control groups of subjects that is accompanied with a reliable elevation of caspases-1,-3,-8. The combined effects of glutargin and erbisol in patients of this group are characterized by a decrease (but not a normalization) of the blood content of sCD95 by 45 %, sFas-l by – 46 %, sCD117 – by 47 % and a decrease of the activity of caspases-1,-3,-8.ru_RU
dc.language.isootherru_RU
dc.subjectвегето-судинна дистоніяru_RU
dc.subjectапоптозru_RU
dc.subjectглутаргінru_RU
dc.subjectербісолru_RU
dc.subjectvegetovascular dystoniaru_RU
dc.subjectapoptosisru_RU
dc.subjectglutarginru_RU
dc.subjecterbisolru_RU
dc.subjectвегето-сосудистая дистонияru_RU
dc.subjectглутаргинru_RU
dc.subjectэрбисолru_RU
dc.titleЗміни концентрації в плазмі крові маркерів апоптозу ендотеліоцитів у хворих на вегето-судинну дистонію та методи їх корекціїru_RU
dc.typeArticleru_RU
Appears in Collections:Статті. Кафедра нервових хвороб, психіатрії та медичної психології ім. С.М. Савенка

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