Sex related peculiarities of the adrenal tissue response on the hypobaric hypoxia at the altered duration of photoperiod in immature rats

Abstract

This study showed the sex related dependence of the reaction of proteolytic processes in tissues of the adrenal glands of male and female immature rats held in systemic intermittent hypobaric hypoxia and constant lighting. The modelling of hypobaric hypoxia combined with a varying length of the photoperiod (natural duration of photoperiod and constant lighting) causes a different changes of the proteolysis in the tissues of the adrenal glands of the male and female immature rats with varying intensity depending on the sex of animals and duration of photoperiod. Sex differences in the response of tissue proteolysis indicators in the main organ of adaptation process in immature animals indicate a genetic-dependent peculiarities of reactivity of the response mechanisms of the body on the action of environmental factors at their isolated and combined impact.