The role of clinical anamnestic indices in diagnostics of sever persisting bronchial asthma in children

Abstract

Performed integral estimation of the diagnostic value of the obtained clinicalparaclinical parameters is indicative of a sufficient amount of reliable markers in verification of severe bronchial asthma (BA) in children. Children with severe bronchial asthma are characterized by the following phenotype peculiarities: early debut of the disease (chance ratio (CR) = 1,5 (95% confidence interval (CI) 0,9-2,7), comorbid allergic diseases available (allergic rhinitis and atopic dermatitis) (CR 2,7 (95% CI 1,5-4,8) and drug-induced or comorbid drug-induced and food or domestic allergy (CR=4,8 (95% CІ 0,1-36,5)), infectious index more than 2 (CR=3,3 (95% CІ 1,6-6,7), seasonal exacerbation of BA mainly from November to March (СR=2,7 (95% CІ 1,5-4,9), associated with a trigger role of acute respiratory viral infection (ARVI) (СR=5,5 (95% CІ 2,4-12,6) and meteorological factors (СR=3,8 (95% CІ 0,4-36,4)