MICROFLORA OF PANCREATIC TISSUE, PERITONEAL CAVITY (BURSA OMENTALIS) AND PERIPHERAL BLOOD IN PATIENTS WITH DESTRUCTIVE PANCREATITIS: ABDOMINAL SEPSIS FORMATION

Abstract

Species composition and population level of pancreatic microflora, peritoneal cavity content and peripheral blood of patients with destructive forms of acute pancreatitis, complicated by the abdominal sepsis were investigated. Bacteriaemia was found in 77.8% of patients; main pathogens in injured pancreatic gland were Escherichia coli and Staphylococcus aureus, their pathogenetic role preserved in the development of peritoneal inflammation and septic state, increasing due to conditionally pathogenic microorganisms-associates. Basic source of microorganisms’ translocation and abdominal sepsis development in case of acute pancreatitis was microflora of infected pancreatic gland and peritoneal cavity to a lesser extent.